Cancer Risk Associated With Abortion - Revision history

Barb: /* Induced Abortion as an Independent Risk Factor For Breast Cancer */

2025-06-13T14:36:25Z

Induced Abortion as an Independent Risk Factor For Breast Cancer

← Older revision		Revision as of 09:36, 13 June 2025
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	Conclusion		Conclusion

			In summary, we have found genetic and lifestyle risk predictors for breast cancer with moderate discrimination, which might provide reference for breast cancer screening in southeast China. Further population-based studies are needed to validate the model for future applications in personalized breast cancer screening programs.</blockquote>'''[https://doi.org/10.1155/2022/6700688 A Meta-Analysis of Induced Abortion, Alcohol Consumption, and Smoking Triggering Breast Cancer Risk among Women from Developed and Least Developed Countries]. Islam, M. A., Sathi, N. J., Abdullah, H. M., & Tabassum, T. (2022). ''International Journal of Clinical Practice,'' 2022, 6700688.''' <blockquote>''Background''. The most prominent form of cancer in women is breast cancer, and modifiable lifestyle risk factors, including smoking, alcohol consumption, and induced abortion, can all contribute significantly to this disease. ''Objectives''. This study’s primary purpose was to assess the prevalence of breast cancer among women in developed and developing countries and the association between three modifiable hazard factors (induced abortion, smoking behavior, and alcohol use) and breast cancer. ''Methods''. This study performed a systematic literature database review up to September 21, 2021. We employed meta-analytic tools such as the random effects model, forest plot, and subgroup analysis to conduct the research. Additionally, we conducted a sensitivity analysis to assess the influence of outliers. ''Results''. According to the random effects model, smoker women have a higher risk of developing breast cancer from different countries (OR = 1.46; 95% CI: 1.08–1.97). In the case of induced abortion, the pooled estimate (OR = 1.25; 95% CI: 1.01–1.53) indicated a significant link between abortion and breast cancer. Subgroup analysis revealed that smoking substantially influences breast cancer in developing and developed countries. Breast cancer was more common among women who smoked in developed countries than in developing nations. ''Conclusion''. The observed findings give sufficient support for the hypothesis that smoking and abortion have a significant influence on breast cancer in different nations. Health organizations should individually design comprehensive scientific plans to raise awareness about the risks of abortion and smoking in developed and developing countries.</blockquote>'''[https://pmc.ncbi.nlm.nih.gov/articles/PMC6445797/ Induced Abortion, Birth Control Methods, and Breast Cancer Risk: A Case-Control Study in China.] Yuan X, Yi F, Hou C, Lee H, Zhong X, Tao P, Li H, Xu Z, Li J. J Epidemiol. 2019 May 5;29(5):173-179. doi: 10.2188/jea.JE20170318. Epub 2018 Aug 11. PMID: 30101815; PMCID: PMC6445797.'''<blockquote>Background
	In summary, we have found genetic and lifestyle risk predictors for breast cancer with moderate discrimination, which might provide reference for breast cancer screening in southeast China. Further population-based studies are needed to validate the model for future applications in personalized breast cancer screening programs.</blockquote>'''[https://pmc.ncbi.nlm.nih.gov/articles/PMC6445797/ Induced Abortion, Birth Control Methods, and Breast Cancer Risk: A Case-Control Study in China.] Yuan X, Yi F, Hou C, Lee H, Zhong X, Tao P, Li H, Xu Z, Li J. J Epidemiol. 2019 May 5;29(5):173-179. doi: 10.2188/jea.JE20170318. Epub 2018 Aug 11. PMID: 30101815; PMCID: PMC6445797.'''<blockquote>Background

	The association between induced abortion and birth control methods (including oral contraceptives and intrauterine devices) and breast cancer may vary among countries, due to the different usage and frequency of birth control methods and induced abortion among countries. A better understanding of this association may help in determining safer birth control methods for Chinese women.		The association between induced abortion and birth control methods (including oral contraceptives and intrauterine devices) and breast cancer may vary among countries, due to the different usage and frequency of birth control methods and induced abortion among countries. A better understanding of this association may help in determining safer birth control methods for Chinese women.
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	Conclusion		Conclusion
			The relationship between induced abortion and birth control methods and breast cancer was complex, though being exposed to induced abortion and two or more birth control methods in one’s lifetime appeared to be risk factors for breast cancer in Chinese women.</blockquote>'''[https://doi.org/10.1186/s12905-017-0368-0 Reproductive risk factors associated with breast cancer in women in Bangui: a case-control study]. Balekouzou, A., Yin, P., Pamatika, C. M., Bekolo, C. E., Nambei, S. W., Djeintote, M., Kota, K., Mossoro-Kpinde, C. D., Shu, C., Yin, M., Fu, Z., Qing, T., Yan, M., Zhang, J., Chen, S., Li, H., Xu, Z., & Koffi, B. (2017). BMC Women's Health, 17(1), 14.''' <blockquote>
			=== Background ===
			Breast cancer (breast Ca) is recognized as a major public health problem in the world. Data on reproductive factors associated with breast Ca in the Central African Republic (CAR) is very limited. This study aimed to identify reproductive variables as risk factors for breast Ca in CAR women.

			=== Methods ===
			A case–control study was conducted among 174 cases of breast Ca confirmed at the Pathology Unit of the National Laboratory in Bangui between 2003 and 2015 and 348 age-matched controls. Data collection tools included a questionnaire, interviews and a review of medical records of patients. Data were analysed using SPSS software version 20. Odd ratios and 95% confidence intervals (CI) for the likelihood of developing breast Ca were obtained using unconditional logistic regression.

			=== Results ===
			In total, 522 women with a mean age of 45.8 (SD = 13.4) years were enrolled. Women with breast Ca were more likely to have attained little or no education (AOR = 11.23, CI: 4.65–27.14 and AOR = 2.40, CI: 1.15–4.99), to be married (AOR = 2.09, CI: 1.18–3.71), '''to have had an abortion (AOR = 5.41, CI: 3.47–8.44'''), and to be nulliparous (AOR = 1.98, CI: 1.12–3.49). Decreased odds of breast Ca were associated with being employed (AOR = 0.32, CI: 0.19–0.56), living in urban areas (AOR = 0.16, CI: 0.07–0.37), late menarche (AOR = 0.18, CI: 0.07–0.44), regular menstrual cycles (AOR = 0.44, CI: 0.23–0.81), term pregnancy (AOR = 0.26, CI: 0.13–0.50) and hormonal contraceptive use (AOR = 0.62, CI: 0.41–0.93).

			=== Conclusion ===
			Breast Ca risk factors in CAR did not appear to be significantly different from that observed in other populations. This study highlighted the risk factors of breast Ca in women living in Bangui to inform appropriate control measures.</blockquote>


	The relationship between induced abortion and birth control methods and breast cancer was complex, though being exposed to induced abortion and two or more birth control methods in one’s lifetime appeared to be risk factors for breast cancer in Chinese women.</blockquote>[https://onlinelibrary.wiley.com/doi/10.1002/cam4.6198 Breast cancer risk assessment using genetic variants and risk factors in a Singapore Chinese population.] Lee CP, Irwanto A, Salim A, Yuan JM, Liu J, Koh WP, Hartman M. Breast Cancer Res. 2014 Jun 18;16(3):R64. doi: 10.1186/bcr3678. PMID: 24941967; PMCID: PMC4095592.		'''[https://onlinelibrary.wiley.com/doi/10.1002/cam4.6198 Breast cancer risk assessment using genetic variants and risk factors in a Singapore Chinese population.] Lee CP, Irwanto A, Salim A, Yuan JM, Liu J, Koh WP, Hartman M. Breast Cancer Res. 2014 Jun 18;16(3):R64. doi: 10.1186/bcr3678. PMID: 24941967; PMCID: PMC4095592.'''

	* Background: Despite the rising incidence and mortality of breast cancer among women in China, there are currently few predictive models for breast cancer in the Chinese population and with low accuracy. This study aimed to identify major genetic and life-style risk factors in a Chinese population for potential application in risk assessment models.		* Background: Despite the rising incidence and mortality of breast cancer among women in China, there are currently few predictive models for breast cancer in the Chinese population and with low accuracy. This study aimed to identify major genetic and life-style risk factors in a Chinese population for potential application in risk assessment models.
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	'''[https://pubmed.ncbi.nlm.nih.gov/25189013/ Normal breast physiology: the reasons hormonal contraceptives and induced abortion increase breast-cancer risk.] Lanfranchi A. Issues Law Med. 2014 Spring;29(1):135-46. PMID: 25189013.'''<blockquote>Abstract		'''[https://pubmed.ncbi.nlm.nih.gov/25189013/ Normal breast physiology: the reasons hormonal contraceptives and induced abortion increase breast-cancer risk.] Lanfranchi A. Issues Law Med. 2014 Spring;29(1):135-46. PMID: 25189013.'''<blockquote>Abstract

	A woman gains protection from breast cancer by completing a full-term pregnancy. In utero, her offspring produce hormones that mature 85 percent of the mother's breast tissue into cancer-resistant breast tissue. If the pregnancy ends through an induced abortion or a premature birth before thirty-two weeks, the mother's breasts will have only partially matured, retaining even more cancer-susceptible breast tissue than when the pregnancy began. This increased amount of immature breast tissue will leave the mother with more sites for cancer initiation, thereby increasing her risk of breast cancer. Hormonal contraceptives increase breast-cancer risk by their proliferative effect on breast tissue and their direct carcinogenic effects on DNA. Hormonal contraceptives include estrogen-progestin combination drugs prescribed in any manner of delivery: orally, transdermally, vaginally, or intrauterine. This article provides the detailed physiology and data that elucidate the mechanisms through which induced abortion and hormonal contraceptives increase breast-cancer risk.</blockquote>'''[http://link.springer.com/article/10.1007/s10552-013-0325-7 A meta-analysis of the association between induced abortion and breast cancer risk among Chinese females.] Yubei Huang, et al. Cancer Causes & Control November 2013'''<blockquote>'''Results:''' A total of 36 articles (two cohort studies and 34 case–control studies) covering 14 provinces in China were included in this review. Compared to people without any history of IA, an increased risk of breast cancer was observed among females who had at least one IA (OR = 1.44, 95 % CI 1.29–1.59, I 2 = 82.6 %, p < 0.001, n = 34). No significant publication bias was found among the included studies (Egger test, p = 0.176). The risk increased to 1.76 (95 % CI 1.39–2.22) and 1.89 (95 % CI 1.40–2.55) for people who had at least two IAs and at least three IAs, respectively. Subgroup analyses showed similar results to the primary results. Meta-regression analysis of the included studies found that the association between IA and breast cancer risk attenuated with increasing percent of IA in the control group (β = −0.022, p < 0.001). '''Conclusion:''' IA is significantly associated with an increased risk of breast cancer among Chinese females, and the risk of breast cancer increases as the number of IA increases. If IA were to be confirmed as a risk factor for breast cancer, high rates of IA in China may contribute to increasing breast cancer rates.</blockquote>[http://bcpinstitute.org/epidemiology_studies_bcpi.htm Epidemiologic Studies: Induced Abortion and Breast Cancer Risk]		A woman gains protection from breast cancer by completing a full-term pregnancy. In utero, her offspring produce hormones that mature 85 percent of the mother's breast tissue into cancer-resistant breast tissue. If the pregnancy ends through an induced abortion or a premature birth before thirty-two weeks, the mother's breasts will have only partially matured, retaining even more cancer-susceptible breast tissue than when the pregnancy began. This increased amount of immature breast tissue will leave the mother with more sites for cancer initiation, thereby increasing her risk of breast cancer. Hormonal contraceptives increase breast-cancer risk by their proliferative effect on breast tissue and their direct carcinogenic effects on DNA. Hormonal contraceptives include estrogen-progestin combination drugs prescribed in any manner of delivery: orally, transdermally, vaginally, or intrauterine. This article provides the detailed physiology and data that elucidate the mechanisms through which induced abortion and hormonal contraceptives increase breast-cancer risk.</blockquote>'''[http://link.springer.com/article/10.1007/s10552-013-0325-7 A meta-analysis of the association between induced abortion and breast cancer risk among Chinese females.] Yubei Huang, et al. Cancer Causes & Control November 2013'''<blockquote>'''Results:''' A total of 36 articles (two cohort studies and 34 case–control studies) covering 14 provinces in China were included in this review. Compared to people without any history of IA, an increased risk of breast cancer was observed among females who had at least one IA (OR = 1.44, 95 % CI 1.29–1.59, I 2 = 82.6 %, p < 0.001, n = 34). No significant publication bias was found among the included studies (Egger test, p = 0.176). The risk increased to 1.76 (95 % CI 1.39–2.22) and 1.89 (95 % CI 1.40–2.55) for people who had at least two IAs and at least three IAs, respectively. Subgroup analyses showed similar results to the primary results. Meta-regression analysis of the included studies found that the association between IA and breast cancer risk attenuated with increasing percent of IA in the control group (β = −0.022, p < 0.001). '''Conclusion:''' IA is significantly associated with an increased risk of breast cancer among Chinese females, and the risk of breast cancer increases as the number of IA increases. If IA were to be confirmed as a risk factor for breast cancer, high rates of IA in China may contribute to increasing breast cancer rates.</blockquote>'''[https://doi.org/10.7314/apjcp.2012.13.1.033 Abortions and breast cancer risk in premenopausal and postmenopausal women in Jiangsu Province of China]. Jiang, A. R., Gao, C. M., Ding, J. H., Li, S. P., Liu, Y. T., Cao, H. X., Wu, J. Z., Tang, J. H., Qian, Y., & Tajima, K. (2012). ''Asian Pacific Journal of Cancer Prevention:'' APJCP, 13(1), 33–35.''' <blockquote>To evaluate the relationship between abortions and risk of breast cancer, we conducted a case-control study with 669 cases and 682 population-based controls in Jiangsu Province of China. A structured questionnaire was used to elicit detailed information. Unconditional logistic regression analysis was performed to calculate odds ratios (ORs) and 95% confidence intervals (CIs). The results have revealed that induced abortion was related to increased risk of breast caner. Premenopausal women who had ${\geq}3$ times of induced abortion were at increased crude OR (2.41, 95%CI: 1.09-5.42) and adjusted-OR (1.55, 95%CI: 1.15-5.68). Postmenopausal women with a previous induced abortion were at increased crude OR (2.04, 95%CI: 1.48-2.81) and adjusted-OR (1.82, 95%CI: 1.30-2.54), and there was a significant increase trend in OR with number of induced abortions (p for trend: 0.0001). Overall, spontaneous abortion did not significantly alter the risk of breast cancer, but postmenopausal women who had history of spontaneous abortion were at increased OR. These results suggested that relationship between breast cancer and abortions may depend on menopausal status and induced abortion may played an important role in the development of breast cancer in Jiangsu' women of China.</blockquote>[http://bcpinstitute.org/epidemiology_studies_bcpi.htm Epidemiologic Studies: Induced Abortion and Breast Cancer Risk]

	:This fact sheet identifies 73 studies (and counting) that examine abortion and breast cancer, listing the studies and their results.		:This fact sheet identifies 73 studies (and counting) that examine abortion and breast cancer, listing the studies and their results.

Barb: /* Induced Abortion as an Independent Risk Factor For Breast Cancer */

2025-06-03T23:27:43Z

Induced Abortion as an Independent Risk Factor For Breast Cancer

← Older revision		Revision as of 18:27, 3 June 2025
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	'''''[https://pubmed.ncbi.nlm.nih.gov/19336554/ Risk factors for triple-negative breast cancer in women under the age of 45 years]. Dolle J, Daling J, White E, Brinton L, Doody D, et al. Cancer Epidemiol Biomarkers Prev 2009;18(4)1157-1166.'''''		'''''[https://pubmed.ncbi.nlm.nih.gov/19336554/ Risk factors for triple-negative breast cancer in women under the age of 45 years]. Dolle J, Daling J, White E, Brinton L, Doody D, et al. Cancer Epidemiol Biomarkers Prev 2009;18(4)1157-1166.'''''
	:In a reversal of the NCI panel opinion that abortion was not linked breast cancer, this new study (including leading researchers who previously questioned the link) identifies abortion as a consistent risk factor, associated with a 40% increased risk of abortion. See [http://www.abortionbreastcancer.com/download/Brind_Dolle_2009_analysis.PDF Brind.]		:In a reversal of the NCI panel opinion that abortion was not linked breast cancer, this new study (including leading researchers who previously questioned the link) identifies abortion as a consistent risk factor, associated with a 40% increased risk of abortion. See [https://web.archive.org/web/20160303165430/http://www.abortionbreastcancer.com/download/Brind_Dolle_2009_analysis.PDF Brind.]

Barb at 23:23, 3 June 2025

2025-06-03T23:23:35Z

Show changes

Barb: /* Induced Abortion as an Independent Risk Factor For Breast Cancer */

2025-06-03T23:15:21Z

Induced Abortion as an Independent Risk Factor For Breast Cancer

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 ===Induced Abortion as an Independent Risk Factor For Breast Cancer===
-[https://onlinelibrary.wiley.com/doi/10.1002/cam4.6198 Breast cancer risk assessment using genetic variants and risk factors in a Singapore Chinese population.] Lee CP, Irwanto A, Salim A, Yuan JM, Liu J, Koh WP, Hartman M. Breast Cancer Res. 2014 Jun 18;16(3):R64. doi: 10.1186/bcr3678. PMID: 24941967; PMCID: PMC4095592.
+=== Methods ===
 * Background: Despite the rising incidence and mortality of breast cancer among women in China, there are currently few predictive models for breast cancer in the Chinese population and with low accuracy. This study aimed to identify major genetic and life-style risk factors in a Chinese population for potential application in risk assessment models.

WikiSysop: /* Induced Abortion as an Independent Risk Factor For Breast Cancer */

2024-02-07T22:43:27Z

Induced Abortion as an Independent Risk Factor For Breast Cancer

← Older revision		Revision as of 17:43, 7 February 2024
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	===Induced Abortion as an Independent Risk Factor For Breast Cancer===		===Induced Abortion as an Independent Risk Factor For Breast Cancer===

			[https://onlinelibrary.wiley.com/doi/10.1002/cam4.6198 Breast cancer risk assessment using genetic variants and risk factors in a Singapore Chinese population.] Lee CP, Irwanto A, Salim A, Yuan JM, Liu J, Koh WP, Hartman M. Breast Cancer Res. 2014 Jun 18;16(3):R64. doi: 10.1186/bcr3678. PMID: 24941967; PMCID: PMC4095592.

			* Background: Despite the rising incidence and mortality of breast cancer among women in China, there are currently few predictive models for breast cancer in the Chinese population and with low accuracy. This study aimed to identify major genetic and life-style risk factors in a Chinese population for potential application in risk assessment models.
			* Methods: A case–control study in southeast China was conducted including 1321 breast cancer patients and 2045 controls during 2013–2016, in which the data were randomly divided into a training set and a test set on a 7:3 scale. The association between genetic and life-style factors and breast cancer was examined using logistic regression models. Using AUC curves, we also compared the performance of the logistic model to machine learning models, namely LASSO regression model and support vector machine (SVM), and the scores calculated from CKB, Gail and Tyrer–Cuzick models in the test set.
			* Results: Among all factors considered, the best model was achieved when polygenetic risk score, lifestyle, and reproductive factors were considered jointly in the logistic regression model (AUC = 0.73; 95% CI: 0.70–0.77). The models created in this study performed better than those using scores calculated from the CKB, Gail, and Tyrer–Cuzick models. However, the logistic model and machine learning models did not significantly differ from one another.
			* Conclusion: In summary, we have found genetic and lifestyle risk predictors for breast cancer with moderate discrimination, which might provide reference for breast cancer screening in southeast China. Further population-based studies are needed to validate the model for future applications in personalized breast cancer screening programs.
			* Editor notes: Abortion was the strongest risk factors. The study found women with 2 or more abortions had 7 times the rate of breast cancer of women who had less than 2 abortions, Most of the abortions were mifepristone medical abortions.

	[http://link.springer.com/article/10.1007/s10552-013-0325-7 A meta-analysis of the association between induced abortion and breast cancer risk among Chinese females.] Yubei Huang, et al. Cancer Causes & Control November 2013		[http://link.springer.com/article/10.1007/s10552-013-0325-7 A meta-analysis of the association between induced abortion and breast cancer risk among Chinese females.] Yubei Huang, et al. Cancer Causes & Control November 2013

Barb: /* Induced Abortion as an Independent Risk Factor For Breast Cancer */

2017-05-30T21:04:09Z

Induced Abortion as an Independent Risk Factor For Breast Cancer

← Older revision		Revision as of 16:04, 30 May 2017
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	:'''Conclusion:''' IA is significantly associated with an increased risk of breast cancer among Chinese females, and the risk of breast cancer increases as the number of IA increases. If IA were to be confirmed as a risk factor for breast cancer, high rates of IA in China may contribute to increasing breast cancer rates.		:'''Conclusion:''' IA is significantly associated with an increased risk of breast cancer among Chinese females, and the risk of breast cancer increases as the number of IA increases. If IA were to be confirmed as a risk factor for breast cancer, high rates of IA in China may contribute to increasing breast cancer rates.

	[http://bcpinstitute.org/~~FactSheets/BCPI-FactSheet-Epidemiol-studies_8_8_2013~~.~~pdf~~ Epidemiologic Studies: Induced Abortion and Breast Cancer Risk]		[http://bcpinstitute.org/epidemiology_studies_bcpi.htm Epidemiologic Studies: Induced Abortion and Breast Cancer Risk]

	:This fact sheet identifies 73 studies (and counting) that examine abortion and breast cancer, listing the studies and their results.		:This fact sheet identifies 73 studies (and counting) that examine abortion and breast cancer, listing the studies and their results.

Barb: /* Induced Abortion as an Independent Risk Factor For Breast Cancer */

2014-01-08T19:35:46Z

Induced Abortion as an Independent Risk Factor For Breast Cancer

← Older revision		Revision as of 14:35, 8 January 2014
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	===Induced Abortion as an Independent Risk Factor For Breast Cancer===		===Induced Abortion as an Independent Risk Factor For Breast Cancer===

			[http://link.springer.com/article/10.1007/s10552-013-0325-7 A meta-analysis of the association between induced abortion and breast cancer risk among Chinese females.] Yubei Huang, et al. Cancer Causes & Control November 2013
			:'''Results:''' A total of 36 articles (two cohort studies and 34 case–control studies) covering 14 provinces in China were included in this review. Compared to people without any history of IA, an increased risk of breast cancer was observed among females who had at least one IA (OR = 1.44, 95 % CI 1.29–1.59, I 2 = 82.6 %, p < 0.001, n = 34). No significant publication bias was found among the included studies (Egger test, p = 0.176). The risk increased to 1.76 (95 % CI 1.39–2.22) and 1.89 (95 % CI 1.40–2.55) for people who had at least two IAs and at least three IAs, respectively. Subgroup analyses showed similar results to the primary results. Meta-regression analysis of the included studies found that the association between IA and breast cancer risk attenuated with increasing percent of IA in the control group (β = −0.022, p < 0.001).
			:'''Conclusion:''' IA is significantly associated with an increased risk of breast cancer among Chinese females, and the risk of breast cancer increases as the number of IA increases. If IA were to be confirmed as a risk factor for breast cancer, high rates of IA in China may contribute to increasing breast cancer rates.

	[http://bcpinstitute.org/FactSheets/BCPI-FactSheet-Epidemiol-studies_8_8_2013.pdf Epidemiologic Studies: Induced Abortion and Breast Cancer Risk]		[http://bcpinstitute.org/FactSheets/BCPI-FactSheet-Epidemiol-studies_8_8_2013.pdf Epidemiologic Studies: Induced Abortion and Breast Cancer Risk]
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	:This fact sheet identifies 73 studies (and counting) that examine abortion and breast cancer, listing the studies and their results.		:This fact sheet identifies 73 studies (and counting) that examine abortion and breast cancer, listing the studies and their results.

			Reproductive factors and breast cancer: A case-control study in tertiary care hospital of North India. Bhadoria A S, Kapil U, Sareen N, Singh P.Indian J Cancer 2013;50:316-21
			:History of abortion was also found to be positively associated with the risk of breast cancer with 6.26 times higher risk in women having a history of abortion. The history of abortions was found to be significantly higher in breast cancer cases as compared to controls, with the Relative Risk (RR) = 6.26 in women having a history of abortion.

	[http://www.banglajol.info/index.php/JDMC/article/viewFile/15628/11078 Breast cancer and some epidemiological factors: A hospital based study.] Jabeen S, et al.Journal of Dhaka Medical College 2013;22(1):61-66.		[http://www.banglajol.info/index.php/JDMC/article/viewFile/15628/11078 Breast cancer and some epidemiological factors: A hospital based study.] Jabeen S, et al.Journal of Dhaka Medical College 2013;22(1):61-66.

Barb: /* Induced Abortion as an Independent Risk Factor For Breast Cancer */

2013-09-26T14:08:34Z

Induced Abortion as an Independent Risk Factor For Breast Cancer

← Older revision		Revision as of 09:08, 26 September 2013
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	===Induced Abortion as an Independent Risk Factor For Breast Cancer===		===Induced Abortion as an Independent Risk Factor For Breast Cancer===

			[http://bcpinstitute.org/FactSheets/BCPI-FactSheet-Epidemiol-studies_8_8_2013.pdf Epidemiologic Studies: Induced Abortion and Breast Cancer Risk]

			:This fact sheet identifies 73 studies (and counting) that examine abortion and breast cancer, listing the studies and their results.


			[http://www.banglajol.info/index.php/JDMC/article/viewFile/15628/11078 Breast cancer and some epidemiological factors: A hospital based study.] Jabeen S, et al.Journal of Dhaka Medical College 2013;22(1):61-66.

			:A twenty fold increased risk of breast cancer was associated with a history of abortion in this case-control study of Bengali women.


	'''[http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZHLU200701004.htm Meta-analysis of the Relationship between Abortion and Female Breast Cancer in China] Zhou, et al. Bulletin of Chinese Cancer. 2007. 1:11-13.'''		'''[http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZHLU200701004.htm Meta-analysis of the Relationship between Abortion and Female Breast Cancer in China] Zhou, et al. Bulletin of Chinese Cancer. 2007. 1:11-13.'''

Barb: /* Cervical Cancer */

2012-04-20T16:21:09Z

Cervical Cancer

← Older revision		Revision as of 11:21, 20 April 2012
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	==Cervical Cancer==		==Cervical Cancer==
	:Human papillomavirus infection (HPV) has been identified as the cause of cervical cancer. A contributing factor for cervical cancer is smoking. It is known that postabortion women will smoke more cigarettes than women with other reproductive outcomes. Thus, induced abortion may have an indirect role in the development of cervical cancer.		:Human papillomavirus infection (HPV) has been identified as the cause of cervical cancer. A contributing factor for cervical cancer is smoking. It is known that postabortion women will smoke more cigarettes than women with other reproductive outcomes. Thus, induced abortion may have an indirect role in the development of cervical cancer.


			''Determinants of cervical human papillomavirus infection:differences between high and low onocogenic risk types, PK Chang et al, J Infect Dis 185(1):28, 2002.''

			:A survey of Hong Kong women who participated in cervical cancer screening found that the overall prevalence of HPV was 7.3%. Previous induced abortion was an 87% statistically significant increased risk for HPV for women at high risk for HPV, a 51% statistically significant increased risk for women with any HPV, and a 97% statistically significant increased risk for women with unknown risk for HPV. Other risk factors for HPV included lifetime number of sexual partners, smoking, and having smokers in the family.


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	''"Abnormal Cervical Cytology in Sexually Active Adolescents," Joseph F. Russo and Damell Jones, Journal of Adolescent Health Care 5: 269-271(1984). ''		''"Abnormal Cervical Cytology in Sexually Active Adolescents," Joseph F. Russo and Damell Jones, Journal of Adolescent Health Care 5: 269-271(1984). ''
	:Pap smears on 1,207 sexually active adolescents in a public health department of eastern North Carolina turned up 11% with abnormal findings. Seventy-two percent of those women evaluated by colposcopy with directed biopsies had cervical intraepithelial neoplasia.		:Pap smears on 1,207 sexually active adolescents in a public health department of eastern North Carolina turned up 11% with abnormal findings. Seventy-two percent of those women evaluated by colposcopy with directed biopsies had cervical intraepithelial neoplasia.


	==Ovarian Cancer==		==Ovarian Cancer==

Barb: /* Induced Abortion as an Independent Risk Factor For Breast Cancer */

2010-11-08T16:16:41Z

Induced Abortion as an Independent Risk Factor For Breast Cancer

← Older revision		Revision as of 11:16, 8 November 2010
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	===Induced Abortion as an Independent Risk Factor For Breast Cancer===		===Induced Abortion as an Independent Risk Factor For Breast Cancer===

	'''[http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZHLU200701004.htm Meta-analysis of the Relationship between Abortion and Female Breast Cancer in China] Zhou, et al. Bulletin of Chinese Cancer. 2007. 1:11-13.		'''[http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZHLU200701004.htm Meta-analysis of the Relationship between Abortion and Female Breast Cancer in China] Zhou, et al. Bulletin of Chinese Cancer. 2007. 1:11-13.'''
	'''

	[Purpose] To investigate the relationship between abortion and breast cancer in Chinese women. [Methods] The published case-control studies from 1989 to 2005 about correlation of abortion with breast cancer in China were analyzed using Meta-analysis method to assess the comprehensive relationship between abortion and female breast cancer. [Results] Based on the enrolled criteria, 6 articles was searched. The cumulative cases and controls were 1 440 and 1 785 respectively. Significant heterogeneity was detected among the 6 studies (Q=17.03, P0.05). OR of abortion (random effect model) was 2.04 (95% CI: 1.50~2.76). [Conclusions] This meta-analysis suggests a possible association between abortion and female breast cancer. Women with a history of abortion would have 2.04 times risk of being breast cancer than who without history of abortion.		[Purpose] To investigate the relationship between abortion and breast cancer in Chinese women. [Methods] The published case-control studies from 1989 to 2005 about correlation of abortion with breast cancer in China were analyzed using Meta-analysis method to assess the comprehensive relationship between abortion and female breast cancer. [Results] Based on the enrolled criteria, 6 articles was searched. The cumulative cases and controls were 1 440 and 1 785 respectively. Significant heterogeneity was detected among the 6 studies (Q=17.03, P0.05). OR of abortion (random effect model) was 2.04 (95% CI: 1.50~2.76). [Conclusions] This meta-analysis suggests a possible association between abortion and female breast cancer. Women with a history of abortion would have 2.04 times risk of being breast cancer than who without history of abortion.